First English captain to sail the Pacific.

In 1572, Oxenham took part on the raid in Panama which was headed by Sir Francis Drake.
In 1573 Oxenham was second in command, still under Sir Francis Drake, during the march to Panama. According to reports, Drake climbed a tree & saw the Pacific Ocean whereby he vowed: ''besought Almightie God of his goodnesse to give him life and leave to sayle once in an English ship on that sea'' At which Oxenham seconded: ''protested that unlesse our Captaine did beate him from his company he would follow him by Gods grace''.
During the raid, Drake & Oxenham split forces & tried two different approaches to Panama. Oxenham returned before Drake & set sail with two ships & 57 men, including John Butler.
Oxenham made his way to the Atlantic coast to prey on shipping. He spent the winters of 1576-1577 inland. In February 1577, Oxenham (in a pinnace which his men & some escaped African slaves, the Cimarrónes built) via a river entered the Gulf of Panama. They looted the Pearl Islands where they tortured a Franciscan friar. From there they plundered two ships laden with gold & silver headed for Panama.
Leaving the Pacific, they were headed towards the Atlantic when they were attcked by the Spanish. Many of Oxenham's men were killed & the treasure was recaptured. Oxenham & some of his men escaped but were hunted down, captured & taken to Panama in April 1578. A total of 18 Englishmen & 40 Africans. 14 of the Englishmen were hanged, the Africans were returned to slavery & Oxenham, Butler & Thomas Sherwell (all of whom were officers) were taken to Lima, Peru & executed late 1580.

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